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Upneeq® Eye Drops: Benefits, Side Effects & Where to Buy

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Published on Apr 29, 2025 By: WIFH Staff

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Treat Droopy Eyelids With Upneeq® Eye Drops

Are droopy eyelids (ptosis) making your eyes appear tired or uneven? You’re not alone. Many people experience eyelid ptosis due to aging, muscle fatigue, or medical conditions. Thankfully, surgery isn’t the only option. Upneeq® is an FDA-approved prescription eye drop that provides a non-invasive solution to lift the upper eyelid, instantly giving your eyes a more open, refreshed, and youthful look in just minutes.

At WIFH, we offer Upneeq® because we believe in treatments that are not only safe and effective but also help you feel like your best, most confident self. When you get Upneeq® from us, you’re not just buying a product—you’re getting expert guidance, personalized care, and the peace of mind that comes with knowing you’re in good hands. In this guide, we’ll walk you through what Upneeq® is, how it works, what to expect, and why choosing WIFH means you’re choosing quality and care you can trust.

What Is Upneeq®?

Upneeq® is an FDA-approved prescription eye drop that temporarily improves the appearance of droopy eyelids, a condition called blepharoptosis. The eye drops contain an oxymetazoline hydrochloride solution that contracts the muscle in the upper eyelid, resulting in lifted and open eyelids.

These single-dose eye drops are safe to use every day. Highly effective, they begin working within 3-5 minutes after installation, with results lasting up to 8 hours. At WIFH, our patients rave about how quickly and effectively Upneeq® works, and most now can’t live without them.

Upneeq® Risks & Side Effects

At WIFH, your health and safety are our top priorities. Before we provide you with Upneeq®, we carefully screen each patient to ensure it’s the right treatment for you. We ask a few simple questions to check for any history of Sjögren’s syndrome, thyroid eye disease, uncontrolled hypertension, or if you’re pregnant or breastfeeding. We also want to know if you have any eye conditions like dry eyes, so we can make sure Upneeq® is a good fit for you. This ensures we give you the best, yet safest care possible. Upneeq has an excellent safety profile, with clinical studies showing it to be well-tolerated and effective for most patients.

Using Upneeq® is quick and easy, and you can apply the drops right at home. Once you receive your Upneeq® eye drops—either by mail or in person—you’ll find them in convenient single-use vials. Here’s how to use them:

  1. Open the foil packet and remove a single-use vial.
  2. Wash your hands thoroughly before applying.
  3. Remove your contact lenses if needed.
  4. Shake the vial gently, then apply one drop of Upneeq® to each eye.
  5. Discard the used vial and packet.

If you wear contact lenses, you can safely put them back on in 15 minutes after dropping in your Upneeq®.

Upneeq® Recovery & Aftercare

Upneeq® eye drops are a hassle-free treatment that seamlessly fit into your daily routine. There’s no downtime, and you can easily apply them from the comfort of your home without interrupting your day. Plus, you can use Upneeq® alongside other eye drops. Just be sure to wait 15 minutes after instilling Upneeq® before using any other drops or putting in your contact lenses for the best results.

Benefits of Upneeq® Eye Drops

Whether caused by genetics, aging, or medical conditions, Upneeq® offers an easy and effective way to enhance the appearance of the eyes and restore a more youthful, alert look. Some of the key benefits of Upneeq® include:

  • Lifting the Eyelids for a More Open, Youthful Look: Upneeq® stimulates the levator muscle, which controls eyelid elevation, helping to naturally lift the eyelid without surgery.
  • Makes Eyes Look Wider & More Awake: By gently raising the upper eyelid, Upneeq® creates a brighter, more refreshed eye appearance, reducing the tired or sleepy look associated with ptosis.
  • Enhances Eye Brightness: Upneeq® constricts blood vessels in the eye, which reduces redness and enhances the natural whiteness of the eyes, making them appear clearer and more vibrant.
  • Fast-Acting & Long-Lasting Results: Many users experience visible results within 2-3 minutes, with effects lasting up to 8 hours—making it an ideal solution for special events, workdays, or daily use.
  • Non-Invasive Alternative to Eyelid Surgery: Unlike blepharoplasty (eyelid surgery), which requires downtime and recovery, Upneeq® is a quick, pain-free option for those looking to correct mild to moderate ptosis without going under the knife.
  • Safe & Effective for Most People: Upneeq® is FDA-approved and has been shown to be effective in clinical trials, making it a reliable option for individuals with age-related ptosis, congenital ptosis, or temporary eyelid drooping due to fatigue or strain.

Whether your droopy eyelids are caused by aging, fatigue, or other factors, Upneeq® provides a simple, non-invasive way to lift your eyelids and restore a vibrant, youthful appearance—effortlessly and effectively.

Upneeq® Eye Drops Before and After

FAQs About Upneeq® Eye Drops

The effects of Upneeq® eye drops last for up to 8 hours. Occasionally, you can use Upneeq® twice in 24 hours if the eye drops are wearing off at the end of the day and you have an evening event.

Upneeq® eye drops contain an oxymetazoline hydrochloride solution that contracts the muscle in the upper eyelid, resulting in temporarily lifted and open eyelids.

The price of Upneeq® varies based on the retailer and quantity. Here at WIFH, we sell a 30-day supply of Upneeq® eye drop treatments for $153 (save $27).

Yes, Upneeq® eye drops are safe for most people. However, those who are pregnant or breastfeeding should not use Upneeq. Additionally, people with Sjogren’s syndrome, thyroid eye disease, or uncontrolled hypertension should consult with their doctor if they are considering Upneeq.

To use Upneeq® eye drops, open the foil wrapped and remove the single-use vial. Then, squeeze 1 drop of Upneeq® in each eye, once a day. After applying the eye drops, throw the vial away.

At WIFH in Atlanta, we offer Upneeq® at the following prices:

  • 30-day supply: $153 (save $27)
  • 60-day supply: $288 (save $72)
  • 90-day supply: $405 (save $135)

Ready to get started? You can easily purchase Upneeq® through our online shop for fast and convenient delivery right to your door.

Upneeq® eye drops begin working for most people in as little as 3-5 minutes and last for up to 8 hours.

Get a Virtual or In-Person Upneeq® Consult at WIFH

Ready to see the difference Upneeq® can make? Visit us at WIFH for an in-person consultation and receive a complimentary sample of Upneeq®—so you can experience the results before committing to a full supply! If you’re not in the Atlanta area, no worries! You can purchase Upneeq® eye drops directly from our online shop, and we’ll reach out to schedule a virtual consultation to ensure your candidacy before shipping the product to you.

Sarah Richardson, LME

Sarah Richardson is WIFH’s Lead Medical Aesthetician and manages the skincare side of our practice. She is also an Assistant Cosmetic Laser Practitioner licensed by the Georgia Medical Composite Board. With over 16 years of skin care experience, Sarah specializes in creating customized treatment plans to address our patients’ individualized needs. Through a combination of clinical facials and aesthetic procedures, as well as scientifically effective skin care products, Sarah helps patients achieve a healthy, radiant, and glowing complexion. She is truly passionate about what she does and loves to educate others who are looking to improve their skin’s health.